AN OPIOID ALTERNATIVE
Using topical analgesics such as Biorexo® in first-line treatment
Chronic Pain relief
# neuropathic
conditions
# arthritis
# musculoskeletal
disorders
Topical analgesics are safe, effective for chronic pain.1
The Centers for Disease Control and Prevention (CDC) issued guidance and training modules on prescribing opioids for chronic pain. In module 2, “Treating Chronic Pain with Opioids”, the CDC suggests topical analgesics should be considered a first-line treatment for pain.2
• Less than 1% (0.5%) of patients in the unmatched intervention group reported a skin rash, with no adverse effects or serious adverse effects reported by clinicians at the participating study sites.1
• Examples include: Lidocaine, Capsaicin, Topical Nonsteroidal anti-inflammatory drugs (NSAIDs)2
Topical painkillers, or analgesics, are sprayed on, rubbed in or applied as patches onto the skin over painful muscles or joints.
Although all are designed to relieve pain,
# Reductions in the interference of pain with activities of daily living were also noted. Importantly, the topical compounded formulations were associated with reductions in the use of concurrent pain medications, including oral opioid analgesics. Randomized, controlled trials will confirm the efficacy and safety results reported here.1
The
HAS SHIFTED TO
Lidocaine + Menthol
Pain Relief Patch
Lidocaine
Menthol
Why Lidocaine and Menthol ?
Pain Patch
The Journal of Pain Management
In July 2017, the Journal of Pain Management published a comparison of transdermal OTC Lidocaine 3.6% and Menthol 1.25% with Rx Lidocaine 5% and placebo for back pain and arthritis. 3
The study demonstrated that there was no difference in the levels of pain relief and quality of life between the menthol and lidocaine patch over the counter product and the prescription 5% Rx Lidocaine patch
Use Topical Analgesics for Chronic Pain Relief
Lidocaine Pain Patch
In October 2017, the Journal of Pain Research published a study: “Changes in pain and concurrent pain medication use following compounded topical analgesic treatment for chronic pain: 3- and 6-month follow-up results from the prospective, observational Optimizing Patient Experience and Response to Topical Analgesics study.”1
Patients were all being treated with Rx oral NSAIDs, prescription opioids or both at start of intervention with compounded topical agents;
NSAIDs (eg, naproxen sodium, celecoxib, meloxicam), prescription opioids (eg, fentanyl, hydrocodone, hydromorphone, morphine, or oxycodone).
The key insight to this preliminary study employed compounded topical (Flurbiprofen, Diclofenac Ketoprofen) NSAID creams on moderate to severe pain sufferers of arthritic, musculoskeletal, or neuralgic pain.
Topical analgesics appear to be effective and safe for the treatment of chronic pain, with randomized controlled trials needed to confirm these findings.
Results suggest that the topical analgesics are effective and safe for the relief of moderately severe chronic pain attributed to arthritis, neuropathic conditions, and musculoskeletal disorders.
The study concluded, although preliminary, that topical NSAIDs appear to be safe and effective to treat chronic pain.
Importantly, the study showed a de-escalation of oral Rx NSAID and opioid use:
• Over 50% of opioid users were off opioids at the 6 month mark
• Reductions in the interference of pain with activities of daily living were also noted.
• Importantly, the topical compounded formulations were associated with reductions in the use of concurrent pain medications, including oral opioid analgesics. Randomized, controlled trials will confirm the efficacy and safety results reported here.1
Do you have
commonly experienced in
Every patient with chronic pain must be medically evaluated to determine if the pain is peripheral, central, or a combination of both. Biorexo encourages you to speak to pain specialist doctors and apply a multidisciplinary rehabiliation approach.
Biorexo Guesstimate Success Rate
20%
65%
70%
Increase your pain relief
